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Prolact+ H2MF® - Human Milk Fortifier


Prolact+ H2MF - Redefining HMF as Purely Human Protein™

Prolact+ H2MF is the first and only commercially available human milk fortifier made from concentrated 100% human milk. These formulations are fortified with essential minerals and offer protein delivery up to 3.7g/100mL of fortified milk1 and 24 to 30 Cal/fl oz.

When added to human milk, Prolact+ H2MF was clinically demonstrated to reduce the odds of developing Nectrotizing Enterocolitis by 77% in premature infants weighing ≤1250g at birth when compared to infants receiving human milk fortified with cow's milk-based HMF or, when supply of mother’s own milk was insufficient, preterm infant formula.2

Human Milk Fortifier Product Line



  Prolact+4™
  • Formulated to fortify breast milk to a minimum of 24 Cal/fl oz. and 82 Cal/100 mL*
  • Fortifies breast milk to a target of 2.3g of protein in 100mL of nutrition.3
  • Available in 10mL and 20mL volumes.
Product Insert (10mL | 20mL)    Sample Nutritional Label (10mL | 20mL)
Prolact+4™ Product

  Prolact+6™
  • Formulated to fortify breast milk to a minimum of 26 Cal/fl oz. and 89 Cal/100 mL*
  • Fortifies breast milk to a target of 2.8g of protein in 100mL of nutrition.3
  • Available in a 30mL volume.
Product Insert (30mL)    Sample Nutritional Label (30mL)
Prolact+6™ Product

  Prolact+8™
  • Formulated to fortify breast milk to a minimum of 28 Cal/fl oz. and 97 Cal/100 mL*
  • Fortifies breast milk to a target of 3.2g of protein in 100mL of nutrition.3
  • Available in a 40mL volume.
Product Insert (40mL)    Sample Nutritional Label (40mL)
Prolact+8™ Product

  Prolact+10™
  • Formulated to fortify breast milk to a minimum of 30 Cal/fl oz. and 104 Cal/100 mL*
  • Fortifies breast milk to a target of 3.7g of protein in 100mL of nutrition.3
  • Available in a 50mL volume.
Product Insert (50mL)    Sample Nutritional Label (50mL)
Prolact+10™ Product


*Nutritional values are based on the assumption that mother’s own milk provides 1.4g of protein per 100mL1 and 20 Cal/fl oz.

1Human milk values vary with references used. Preterm human milk values obtained from Meeting the Special Nutrient Needs of Low Birth Weight and Premature Infants in the Hospital (A8100). Columbus, Ohio: Ross Products Division Abbott Laboratories, January 1998, p56.
2Sullivan S, Schanler RJ, Kim JH et al. An exclusively human milk-based diet is associated with a lower rate of necrotizing enterocolitis than a diet of human milk and bovine milk based products. J Pediatr. 2009:156(4):562-567.
3Nutritional Values are based upon averages or target values for Prolact+ family of fortifiers.