Human Milk Oligosaccharides in Prolacta® Products

HMO Overview

Human milk contains many diverse and naturally occurring bioactive substances, including human milk oligosaccharides (HMO). HMO were discovered as a prebiotic “bifidus factor” that serves as a metabolic substrate for Bifidobacterium spp. and shapes intestinal microbiota composition, with health benefits for the breast-fed neonate.1 In modulating the microbiome, HMO counteract dysbiosis in the infant’s intestine, which leads to the prevention of coinciding diseases.

Approximately 200 different HMO with unique structures have been identified to date.2 Human milk contains higher amounts and more complex structures of soluble oligosaccharides than any other mammalian milk.3

HMO are a family of structurally diverse sugars that are highly abundant in and unique to human milk. They constitute the third-most-abundant component in human milk, following lactose and lipids.4 HMO are more abundant than protein in human milk.

Human Milk Oligosaccharides structure

HMO in Prolacta Bioscience Products

All Prolacta Bioscience’s clinically proven, high-quality neonatal nutritional products are 100% human milk-based and contain a full spectrum of HMO that are critical to support the preterm infant’s health and development.

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