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Cost-benefit analysis




Assessing and understanding the clinical value of an Exclusive Human Milk Diet (EHMD)

The clinical complications of prematurity have a significant financial impact.

Complication Average costs per patient (USD)
Bronchopulmonary dysplasia (BPD) $31,565 1
Late-onset sepsis $10,055 1
Retinopathy of prematurity (ROP) requiring surgery Up to $35,7492
Patent ductus arteriosus (patent ductus arteriosus (PDA)) without surgery $49,457 3
Parenteral nutrition (PN) per day $1,436 4
Medical necrotising enterocolitis (NEC) $74,004 5
Surgical Necrotising enterocolitis (NEC) $198,040 5

These values are for illustrative purposes. Cost calculations will vary by hospital. The incremental cost of these morbidities and interventions can substantially increase the cost of a Special Care Baby Unit (NICU) hospitalisation.

Costs vary by hospitals. That is why our certified health economics consultants are available to customise an analysis specific to your hospital. Complete the form below to start that process or call 1.888.776.5228.

Addressing comorbidities of prematurity and their associated costs

A study* published in the journal Breastfeeding Medicine found that an Exclusive Human Milk Diet (EHMD) including Prolacta’s fortifiers, resulted in adjusted cost savings for medical Necrotising enterocolitis (NEC)** and surgical Necrotising enterocolitis (NEC), over and above the average, of $74,004 and $198,040 per infant, respectively. The infants in the exclusive human milk diet (EHMD) group also had lower expected costs of hospitalisation, resulting in net direct savings of $8,167.17 (USD) per infant.5

Another study published in the Journal of Perinatology found 4.5 fewer days of hospitalisation for very low birth weight (VLBW) infants receiving Prolacta’s products as part of an Exclusive Human Milk Diet (EHMD) compared to very low birth weight (VLBW) babies receiving cow milk-based fortifiers.6

*Extremely premature infants, as defined in the study, are those born weighing <1250 grams.

**Necrotising enterocolitis (NEC) is a dangerous and severe complication that often affects extremely preterm infants, in which the intestinal tissue is damaged. Surgical intervention occurs 20% to 40% of Necrotising enterocolitis (NEC) cases. The case fatality rate of Necrotising enterocolitis (NEC) surgery is as high as 50%.7

Hospital cost savings achieved through use of Prolacta’s human milk–based fortifiers

Prolacta’s products help decrease the overall cost of care for very low birth weight (VLBW) infants when used as part of an exclusive human milk diet (EHMD) in the NICU. Despite the added cost of donor human milk and donor milk–derived fortifiers, an Exclusive Human Milk Diet (EHMD) is cost effective.6

Learn more about the clinical value of an Exclusive Human Milk Diet (EHMD)

Clinical evidence

Read peer-reviewed studies and clinical results

Cost studies

Review the cost-focused clinical studies on Prolacta’s 100% Human Milk Diet

Peer support

Gain insights from fellow neonatologists, nurses and dietitians

Speak to a Health Economics Consultant

Implementing an Exclusive Human Milk Diet (EHMD) can prevent costly health complications in premature infants and save the hospital money. Reach out to our health economics consultants who can help review your revenue cycle management and the use of an Exclusive Human Milk Diet (EHMD), as well as address billing and reimbursement topics such as:

  • Diagnosis-Related Group (DRG)
  • Tax Equity and Fiscal Responsibility Act of 1982 (TEFRA)
  • Cost Outlier (high costs or exceptionally long stays)
  • Stop-Loss Insurance consideration
  • Letter of Medical Necessity (pre-authorisation)

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